6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalene-2 (1H)-imwe
| Imiterere y'ibinyabutabire | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalene-2 (1H)-imwe ni amazi abonerana adafite ibara cyangwa umuhondo woroshye, adashonga mu mazi, ashonga muri CHCl3, ububiko bugomba kuba bukonjeshejwe, butandukanijwe n'ibintu birwanya ogisijeni, imiti iribwa, kure y'umuriro, n'isoko y'ubushyuhe. | |
| Porogaramu | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalene-2 (1H)-imweni urwego rw'ibanze rwa Alectinib, inhibitor ikomeye kandi itoranya cyane ya lymphoma kinase (ALK) ishobora guhagarika gatekeeper mutant idashobora kwihanganira, bigatuma ingirabuzimafatizo zigabanuka. | |
| Imiterere ifatika | Ikinyobwa kitagira ibara kugeza ku muhondo | |
| Igihe cyo kubika | Dukurikije ubunararibonye bwacu, ibicuruzwa bishobora kubikwa mu gihe cy'iminsi 12amezi uhereye igihe cyo gutanga iyo bibitswe mu bikoresho bifunze neza, birinzwe urumuri n'ubushyuhe kandi bikabikwa ku bushyuhe buri hagati ya 5 -30°C. | |
| Timiterere isanzwe
| Aho kubira | 354.7±42.0 °C kuri 760 mmHg |
| Aho gusohokera | 168.3±27.9 °C | |
| Misa nyayo | 282.025543 | |
| PSA | 26.30000 | |
| LogP | 3.25 | |
| Umuvuduko w'umwuka | 0.0±0.8 mmHg kuri 25°C | |
| Urutonde rw'Isubiramo | 1.545 | |
| pka | 1.26±0.10 (Byateganijwe) | |
| Gushonga kw'amazi | 50 mg/ml muri CHCl3 | |
Umutekano
Mu gihe ukoresha iki gicuruzwa, kurikiza inama n'amakuru byatanzwe mu rupapuro rw'amakuru y'umutekano kandi ukurikize ingamba zo kwirinda no kubungabunga isuku aho ukorera zihagije mu gukoresha imiti ikoreshwa mu gukora.
Icyitonderwa
Amakuru ari muri iki gitabo ashingiye ku bumenyi n'uburambe dufite ubu. Kubera ibintu byinshi bishobora kugira ingaruka ku itunganywa n'ikoreshwa ry'ibicuruzwa byacu, aya makuru ntakuraho abatunganya ibicuruzwa gukora iperereza ryabo bwite n'ibizamini; ndetse aya makuru ntagaragaza ko hari ubwishingizi bw'umutungo runaka, cyangwa ko ibicuruzwa bikwiriye ku ntego runaka. Ibisobanuro byose, ibishushanyo, amafoto, amakuru, ingano, uburemere, nibindi bitangwa hano bishobora guhinduka nta makuru abanje kandi ntibigire ubwiza bw'amasezerano bw'ibicuruzwa. Ubwiza bw'amasezerano bw'ibicuruzwa buturuka gusa ku byavuzwe mu bisobanuro by'ibicuruzwa. Ni inshingano z'uwakira ibicuruzwa byacu kugenzura ko uburenganzira ubwo aribwo bwose bw'umutungo n'amategeko n'amategeko ariho byubahirizwa.
